354.9K XNAS Volume
XNAS 17 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2025 | 198,399 | 7,228,073 (18%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2025 | 274,622 | 274,622 | - | - | Stock Option (Right to Buy) | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2025 | 48,117 | 172,711 (0%) | 0% | 0 | Common Stock | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2025 | 66,604 | 66,604 | - | - | Stock Option (Right to Buy) | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2025 | 85,067 | 85,067 | - | - | Stock Option (Right to Buy) | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2025 | 61,456 | 213,751 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2025 | 66,221 | 66,221 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2025 | 47,841 | 156,792 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 3.15 per share. | 02 Jan 2025 | 33,841 | 7,029,674 (17%) | 0% | 3.2 | 106,657 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 3.15 per share. | 02 Jan 2025 | 8,633 | 124,594 (0%) | 0% | 3.2 | 27,209 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.15 per share. | 02 Jan 2025 | 10,227 | 152,295 (0%) | 0% | 3.2 | 32,232 | Common Stock |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 3.15 per share. | 02 Jan 2025 | 9,437 | 108,951 (0%) | 0% | 3.2 | 29,743 | Common Stock |
| Michael P Miller | Director | Sale of securities on an exchange or to another person at price $ 3.49 per share. | 12 Aug 2024 | 23,358 | 47,000 (0%) | 0% | 3.5 | 81,466 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 3.70 per share. | 17 Jul 2024 | 21,920 | 7,063,515 (17%) | 0% | 3.7 | 81,128 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 3.70 per share. | 17 Jul 2024 | 3,637 | 133,227 (0%) | 0% | 3.7 | 13,461 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.70 per share. | 17 Jul 2024 | 4,156 | 162,522 (0%) | 0% | 3.7 | 15,382 | Common Stock |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 3.70 per share. | 17 Jul 2024 | 2,598 | 118,388 (0%) | 0% | 3.7 | 9,615 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 3.27 per share. | 02 Jul 2024 | 18,885 | 7,085,435 (18%) | 0% | 3.3 | 61,726 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 3.27 per share. | 02 Jul 2024 | 4,349 | 136,864 (0%) | 0% | 3.3 | 14,215 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.27 per share. | 02 Jul 2024 | 5,295 | 166,678 (0%) | 0% | 3.3 | 17,307 | Common Stock |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 3.27 per share. | 02 Jul 2024 | 6,051 | 120,986 (0%) | 0% | 3.3 | 19,778 | Common Stock |
| Michael P Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2024 | 27,000 | 95,358 (0%) | 0% | 0 | Common Stock | |
| Jay M. Moyes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2024 | 27,000 | 48,322 (0%) | 0% | 0 | Common Stock | |
| Troy E. Wilson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2024 | 27,000 | 27,350 (0%) | 0% | 0 | Common Stock | |
| Adrian Senderowicz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2024 | 27,000 | 27,000 (0%) | 0% | 0 | Common Stock | |
| Allison Dorval | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2024 | 27,000 | 60,000 (0%) | 0% | 0 | Common Stock | |
| Brian M. Stuglik | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2024 | 27,000 | 76,058 (0%) | 0% | 0 | Common Stock | |
| Alessandra Cesano | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2024 | 27,000 | 54,000 (0%) | 0% | 0 | Common Stock | |
| Jay M. Moyes | Director | Sale of securities on an exchange or to another person at price $ 3.34 per share. | 13 Jun 2024 | 22,000 | 21,322 (0%) | 0% | 3.3 | 73,467 | Common Stock |
| Troy E. Wilson | Director | Sale of securities on an exchange or to another person at price $ 3.33 per share. | 13 Jun 2024 | 27,000 | 350 (0%) | 0% | 3.3 | 89,902 | Common Stock |
| Adrian Senderowicz | Director | Sale of securities on an exchange or to another person at price $ 3.33 per share. | 13 Jun 2024 | 27,000 | 0 (0%) | 0% | 3.3 | 89,818 | Common Stock |
| Allison Dorval | Director | Sale of securities on an exchange or to another person at price $ 3.37 per share. | 13 Jun 2024 | 11,000 | 33,000 (0%) | 0% | 3.4 | 37,096 | Common Stock |
| Brian M. Stuglik | Director | Sale of securities on an exchange or to another person at price $ 3.39 per share. | 13 Jun 2024 | 9,900 | 49,058 (0%) | 0% | 3.4 | 33,528 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2024 | 9,047 | 9,047 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2024 | 6,577 | 7,104,320 (18%) | 0% | 0 | Common Stock | |
| Hunt Douglas M. | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 37,894 | 141,213 (0%) | 0% | 0 | Common Stock | |
| Wong F. Alvin | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 43,307 | 141,241 (0%) | 0% | 0 | Common Stock | |
| F. Nougues Maximo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 59,946 | 59,946 | - | - | Stock Option (Right to Buy) | |
| Auerbach Alan H. | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 160,796 | 7,097,743 (18%) | 0% | 0 | Common Stock | |
| H. Auerbach Alan | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 222,573 | 222,573 | - | - | Stock Option (Right to Buy) | |
| Ludwig Jeffrey Jerome | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 27,067 | 127,037 (0%) | 0% | 0 | Common Stock | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 52,452 | 52,452 | - | - | Stock Option (Right to Buy) | |
| Jerome Ludwig Jeffrey | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 37,466 | 37,466 | - | - | Stock Option (Right to Buy) | |
| F. Maximo Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 43,307 | 171,973 (0%) | 0% | 0 | Common Stock | |
| F. Wong Alvin | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2024 | 59,946 | 59,946 | - | - | Stock Option (Right to Buy) | |
| Alan Auerbach H. | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 4.49 per share. | 03 Jan 2024 | 41,396 | 6,936,947 (17%) | 0% | 4.5 | 185,698 | Common Stock |
| Nougues Maximo F. | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.49 per share. | 03 Jan 2024 | 15,682 | 128,666 (0%) | 0% | 4.5 | 70,348 | Common Stock |
| Jeffrey Ludwig Jerome | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 4.49 per share. | 03 Jan 2024 | 12,956 | 99,970 (0%) | 0% | 4.5 | 58,119 | Common Stock |
| Alvin F. Wong | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 4.49 per share. | 03 Jan 2024 | 7,733 | 98,214 (0%) | 0% | 4.5 | 34,689 | Common Stock |
| Douglas Hunt M. | See Remarks | Sale of securities on an exchange or to another person at price $ 4.49 per share. | 03 Jan 2024 | 8,358 | 103,319 (0%) | 0% | 4.5 | 37,493 | Common Stock |
| F. Wong Alvin | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 3.76 per share. | 04 Dec 2023 | 280 | 97,934 (0%) | 0% | 3.8 | 1,053 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 3.31 per share. | 03 Jul 2023 | 60,698 | 6,978,343 (17%) | 0% | 3.3 | 200,983 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 3.31 per share. | 03 Jul 2023 | 7,809 | 111,677 (0%) | 0% | 3.3 | 25,857 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.31 per share. | 03 Jul 2023 | 14,680 | 144,348 (0%) | 0% | 3.3 | 48,608 | Common Stock |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 3.31 per share. | 03 Jul 2023 | 12,103 | 112,926 (0%) | 0% | 3.3 | 40,075 | Common Stock |
| Alvin F. Wong | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 3.31 per share. | 03 Jul 2023 | 6,938 | 105,947 (0%) | 0% | 3.3 | 22,973 | Common Stock |
| Michael P Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2023 | 27,000 | 68,358 (0%) | 0% | 0 | Common Stock | |
| Michael P Miller | Director | Sale of securities on an exchange or to another person at price $ 3.45 per share. | 13 Jun 2023 | 13,500 | 41,358 (0%) | 0% | 3.5 | 46,630 | Common Stock |
| Jay M. Moyes | Director | Sale of securities on an exchange or to another person at price $ 3.45 per share. | 13 Jun 2023 | 22,000 | 16,322 (0%) | 0% | 3.5 | 75,970 | Common Stock |
| Jay M. Moyes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2023 | 27,000 | 43,322 (0%) | 0% | 0 | Common Stock | |
| Troy E. Wilson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2023 | 27,000 | 27,350 (0%) | 0% | 0 | Common Stock | |
| Troy E. Wilson | Director | Sale of securities on an exchange or to another person at price $ 3.45 per share. | 13 Jun 2023 | 27,000 | 350 (0%) | 0% | 3.5 | 93,269 | Common Stock |
| Adrian Senderowicz | Director | Sale of securities on an exchange or to another person at price $ 3.45 per share. | 13 Jun 2023 | 27,000 | 0 (0%) | 0% | 3.5 | 93,280 | Common Stock |
| Adrian Senderowicz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2023 | 27,000 | 27,000 (0%) | 0% | 0 | Common Stock | |
| Allison Dorval | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2023 | 27,000 | 44,000 (0%) | 0% | 0 | Common Stock | |
| Allison Dorval | Director | Sale of securities on an exchange or to another person at price $ 3.45 per share. | 13 Jun 2023 | 10,000 | 17,000 (0%) | 0% | 3.5 | 34,500 | Common Stock |
| Brian M. Stuglik | Director | Sale of securities on an exchange or to another person at price $ 3.46 per share. | 13 Jun 2023 | 9,900 | 31,958 (0%) | 0% | 3.5 | 34,252 | Common Stock |
| Brian M. Stuglik | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2023 | 27,000 | 58,958 (0%) | 0% | 0 | Common Stock | |
| Alessandra Cesano | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Jun 2023 | 27,000 | 27,000 (0%) | 0% | 0 | Common Stock | |
| Alvin F. Wong | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 3.45 per share. | 02 Jun 2023 | 269 | 112,885 (0%) | 0% | 3.4 | 928 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 258,924 | 258,924 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 186,403 | 7,039,041 (17%) | 0% | 0 | Common Stock | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 48,136 | 119,486 (0%) | 0% | 0 | Common Stock | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 66,864 | 66,864 | - | - | Stock Option (Right to Buy) | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 81,399 | 81,399 | - | - | Stock Option (Right to Buy) | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 58,601 | 159,028 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 66,972 | 125,029 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 93,028 | 93,028 | - | - | Stock Option (Right to Buy) | |
| Alvin F. Wong | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 81,399 | 81,399 | - | - | Stock Option (Right to Buy) | |
| Alvin F. Wong | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 58,601 | 113,154 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 4.18 per share. | 03 Jan 2023 | 27,241 | 6,852,638 (17%) | 0% | 4.2 | 113,810 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 4.18 per share. | 03 Jan 2023 | 4,225 | 71,350 (0%) | 0% | 4.2 | 17,652 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.18 per share. | 03 Jan 2023 | 10,499 | 100,427 (0%) | 0% | 4.2 | 43,864 | Common Stock |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 4.18 per share. | 03 Jan 2023 | 6,568 | 58,057 (0%) | 0% | 4.2 | 27,440 | Common Stock |
| Alvin F. Wong | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 4.18 per share. | 03 Jan 2023 | 3,460 | 54,553 (0%) | 0% | 4.2 | 14,456 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 4.40 per share. | 12 Dec 2022 | 568,181 | 6,879,879 (17%) | 1% | 4.4 | 2,499,996 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 4.50 per share. | 02 Dec 2022 | 1,251 | 6,311,698 (16%) | 0% | 4.5 | 5,627 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 4.50 per share. | 02 Dec 2022 | 429 | 75,575 (0%) | 0% | 4.5 | 1,930 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.50 per share. | 02 Dec 2022 | 159 | 110,926 (0%) | 0% | 4.5 | 715 | Common Stock |
| Alvin F. Wong | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 4.50 per share. | 02 Dec 2022 | 514 | 58,013 (0%) | 0% | 4.5 | 2,312 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 2.25 per share. | 02 Nov 2022 | 1,242 | 6,312,949 (16%) | 0% | 2.3 | 2,795 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 2.25 per share. | 02 Nov 2022 | 429 | 76,004 (0%) | 0% | 2.2 | 965 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.25 per share. | 02 Nov 2022 | 163 | 111,085 (0%) | 0% | 2.3 | 367 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 2.34 per share. | 03 Oct 2022 | 1,260 | 6,314,191 (16%) | 0% | 2.3 | 2,943 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 2.34 per share. | 03 Oct 2022 | 435 | 76,433 (0%) | 0% | 2.3 | 1,016 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.33 per share. | 03 Oct 2022 | 165 | 111,248 (0%) | 0% | 2.3 | 385 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 2.59 per share. | 02 Sep 2022 | 1,254 | 6,315,451 (16%) | 0% | 2.6 | 3,247 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 2.59 per share. | 02 Sep 2022 | 433 | 76,868 (0%) | 0% | 2.6 | 1,121 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.59 per share. | 02 Sep 2022 | 164 | 111,413 (0%) | 0% | 2.6 | 425 | Common Stock |
| Michael P Miller | Director | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 09 Aug 2022 | 25,000 | 54,858 (0%) | 0% | 3.6 | 88,793 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 2.89 per share. | 02 Aug 2022 | 1,247 | 6,316,705 (16%) | 0% | 2.9 | 3,604 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 2.89 per share. | 02 Aug 2022 | 429 | 77,301 (0%) | 0% | 2.9 | 1,240 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.89 per share. | 02 Aug 2022 | 161 | 111,577 (0%) | 0% | 2.9 | 465 | Common Stock |
| Alessandra Cesano | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jul 2022 | 100,000 | 100,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 2.63 per share. | 05 Jul 2022 | 26,140 | 6,317,952 (16%) | 0% | 2.6 | 68,787 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 2.63 per share. | 05 Jul 2022 | 3,753 | 77,730 (0%) | 0% | 2.6 | 9,876 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.63 per share. | 05 Jul 2022 | 9,328 | 111,738 (0%) | 0% | 2.6 | 24,547 | Common Stock |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 2.63 per share. | 05 Jul 2022 | 5,835 | 64,625 (0%) | 0% | 2.6 | 15,355 | Common Stock |
| Alvin F. Wong | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 2.63 per share. | 05 Jul 2022 | 2,920 | 58,527 (0%) | 0% | 2.6 | 7,684 | Common Stock |
| Jay M. Moyes | Director | Sale of securities on an exchange or to another person at price $ 2.64 per share. | 16 Jun 2022 | 22,858 | 38,322 (0%) | 0% | 2.6 | 60,370 | Common Stock |
| Troy E. Wilson | Director | Sale of securities on an exchange or to another person at price $ 2.58 per share. | 16 Jun 2022 | 27,858 | 27,350 (0%) | 0% | 2.6 | 71,971 | Common Stock |
| Adrian Senderowicz | Director | Sale of securities on an exchange or to another person at price $ 2.63 per share. | 16 Jun 2022 | 27,858 | 27,000 (0%) | 0% | 2.6 | 73,303 | Common Stock |
| Brian M. Stuglik | Director | Sale of securities on an exchange or to another person at price $ 2.69 per share. | 16 Jun 2022 | 13,000 | 41,858 (0%) | 0% | 2.7 | 34,918 | Common Stock |
| Michael P Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 27,000 | 79,858 (0%) | 0% | 0 | Common Stock | |
| Jay M. Moyes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 27,000 | 61,180 (0%) | 0% | 0 | Common Stock | |
| Troy E. Wilson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 27,000 | 55,208 (0%) | 0% | 0 | Common Stock | |
| Adrian Senderowicz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 27,000 | 54,858 (0%) | 0% | 0 | Common Stock | |
| Allison Dorval | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 27,000 | 27,000 (0%) | 0% | 0 | Common Stock | |
| Brian M. Stuglik | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2022 | 27,000 | 54,858 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 1.94 per share. | 02 Jun 2022 | 1,200 | 6,344,092 (16%) | 0% | 1.9 | 2,333 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 1.94 per share. | 02 Jun 2022 | 417 | 81,483 (0%) | 0% | 1.9 | 811 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 1.92 per share. | 02 Jun 2022 | 162 | 121,066 (0%) | 0% | 1.9 | 311 | Common Stock |
| Alvin F. Wong | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 1.92 per share. | 02 Jun 2022 | 587 | 61,447 (0%) | 0% | 1.9 | 1,129 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 2.32 per share. | 03 May 2022 | 1,263 | 6,345,292 (16%) | 0% | 2.3 | 2,930 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 2.31 per share. | 03 May 2022 | 438 | 81,900 (0%) | 0% | 2.3 | 1,012 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.34 per share. | 03 May 2022 | 165 | 121,228 (0%) | 0% | 2.3 | 386 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.34 per share. | 03 May 2022 | 165 | 121,228 (0%) | 0% | 2.3 | 386 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.34 per share. | 03 May 2022 | 165 | 121,228 (0%) | 0% | 2.3 | 386 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 3.08 per share. | 04 Apr 2022 | 1,198 | 6,346,555 (16%) | 0% | 3.1 | 3,687 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 3.08 per share. | 04 Apr 2022 | 413 | 82,338 (0%) | 0% | 3.1 | 1,271 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.08 per share. | 04 Apr 2022 | 206 | 121,393 (0%) | 0% | 3.1 | 634 | Common Stock |
| Michael P Miller | Director | Sale of securities on an exchange or to another person at price $ 2.80 per share. | 16 Mar 2022 | 25,653 | 52,858 (0%) | 0% | 2.8 | 71,792 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 2.79 per share. | 03 Mar 2022 | 1,792,114 | 6,347,753 (16%) | 4% | 2.8 | 4,999,998 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 168,824 | 4,555,639 (11%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 241,176 | 241,176 | - | - | Stock Option (Right to Buy) | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 32,353 | 32,353 | - | - | Stock Option (Right to Buy) | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 22,647 | 82,751 (0%) | 0% | 0 | Common Stock | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 88,824 | 88,824 | - | - | Stock Option (Right to Buy) | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 62,176 | 121,599 (0%) | 0% | 0 | Common Stock | |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 55,882 | 55,882 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 39,118 | 70,460 (0%) | 0% | 0 | Common Stock | |
| Alvin F. Wong | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 64,118 | 64,118 | - | - | Stock Option (Right to Buy) | |
| Alvin F. Wong | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Mar 2022 | 44,882 | 62,034 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 2.26 per share. | 02 Mar 2022 | 1,294 | 4,386,815 (11%) | 0% | 2.3 | 2,919 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 2.26 per share. | 02 Mar 2022 | 446 | 60,104 (0%) | 0% | 2.3 | 1,009 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.26 per share. | 02 Mar 2022 | 169 | 59,423 (0%) | 0% | 2.3 | 382 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 2.46 per share. | 02 Feb 2022 | 1,316 | 4,388,109 (11%) | 0% | 2.5 | 3,239 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 2.47 per share. | 02 Feb 2022 | 533 | 60,550 (0%) | 0% | 2.5 | 1,317 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.48 per share. | 02 Feb 2022 | 199 | 59,592 (0%) | 0% | 2.5 | 494 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 3.19 per share. | 03 Jan 2022 | 22,875 | 4,389,425 (11%) | 0% | 3.2 | 72,923 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 3.21 per share. | 03 Jan 2022 | 3,707 | 61,083 (0%) | 0% | 3.2 | 11,890 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 3.19 per share. | 03 Jan 2022 | 7,484 | 59,791 (0%) | 0% | 3.2 | 23,871 | Common Stock |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 3.20 per share. | 03 Jan 2022 | 4,727 | 31,342 (0%) | 0% | 3.2 | 15,121 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 2.90 per share. | 02 Dec 2021 | 1,837 | 4,412,300 (11%) | 0% | 2.9 | 5,327 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 2.90 per share. | 02 Dec 2021 | 441 | 64,790 (0%) | 0% | 2.9 | 1,279 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 2.95 per share. | 02 Dec 2021 | 162 | 67,275 (0%) | 0% | 3.0 | 478 | Common Stock |
| Alvin F. Wong | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 2.91 per share. | 02 Dec 2021 | 1,131 | 17,152 (0%) | 0% | 2.9 | 3,294 | Common Stock |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 5.63 per share. | 02 Nov 2021 | 1,795 | 4,414,137 (11%) | 0% | 5.6 | 10,112 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 5.64 per share. | 02 Nov 2021 | 427 | 65,231 (0%) | 0% | 5.6 | 2,409 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.67 per share. | 02 Nov 2021 | 156 | 67,437 (0%) | 0% | 5.7 | 885 | Common Stock |
| Alan H. Auerbach | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 6.15 per share. | 04 Oct 2021 | 1,858 | 4,415,932 (11%) | 0% | 6.2 | 11,433 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 6.15 per share. | 04 Oct 2021 | 443 | 65,658 (0%) | 0% | 6.2 | 2,726 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.20 per share. | 04 Oct 2021 | 161 | 67,593 (0%) | 0% | 6.2 | 998 | Common Stock |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 7.52 per share. | 02 Sep 2021 | 422 | 66,101 (0%) | 0% | 7.5 | 3,174 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 7.53 per share. | 02 Aug 2021 | 1,764 | 4,419,554 (11%) | 0% | 7.5 | 13,286 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 7.53 per share. | 02 Aug 2021 | 420 | 66,523 (0%) | 0% | 7.5 | 3,161 | COMMON STOCK |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 7.54 per share. | 02 Aug 2021 | 154 | 67,909 (0%) | 0% | 7.5 | 1,161 | COMMON STOCK |
| Allison Dorval | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jul 2021 | 108,721 | 108,721 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 8.84 per share. | 02 Jul 2021 | 5,332 | 4,421,318 (11%) | 0% | 8.8 | 47,121 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 9.15 per share. | 02 Jul 2021 | 1,016 | 66,943 (0%) | 0% | 9.2 | 9,298 | COMMON STOCK |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 9.26 per share. | 02 Jul 2021 | 155 | 68,063 (0%) | 0% | 9.3 | 1,435 | COMMON STOCK |
| Alvin F. Wong | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2021 | 90,000 | 90,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Michael P Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 27,858 | 78,511 (0%) | 0% | 0 | COMMON STOCK | |
| Jay M. Moyes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 27,858 | 34,180 (0%) | 0% | 0 | Common Stock | |
| Troy E. Wilson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 27,858 | 28,208 (0%) | 0% | 0 | COMMON STOCK | |
| Adrian Senderowicz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 27,858 | 27,858 (0%) | 0% | 0 | COMMON STOCK | |
| Brian M. Stuglik | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 27,858 | 27,858 (0%) | 0% | 0 | COMMON STOCK | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 27,858 | 40,732 (0%) | 0% | 0 | COMMON STOCK | |
| Adrian Senderowicz | Director | Sale of securities on an exchange or to another person at price $ 11.17 per share. | 11 Jun 2021 | 40,993 | 0 (0%) | 0% | 11.2 | 457,757 | COMMON STOCK |
| Jay M. Moyes | Director | Sale of securities on an exchange or to another person at price $ 11.36 per share. | 10 Jun 2021 | 25,248 | 6,322 (0%) | 0% | 11.4 | 286,860 | Common Stock |
| Ann C. Miller | Director | Sale of securities on an exchange or to another person at price $ 11.43 per share. | 10 Jun 2021 | 12,874 | 12,874 (0%) | 0% | 11.4 | 147,156 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.74 per share. | 02 Jun 2021 | 1,757 | 4,426,650 (11%) | 0% | 10.7 | 18,877 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 10.77 per share. | 02 Jun 2021 | 416 | 67,959 (0%) | 0% | 10.8 | 4,481 | COMMON STOCK |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 10.74 per share. | 02 Jun 2021 | 152 | 68,218 (0%) | 0% | 10.7 | 1,633 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 9.01 per share. | 03 May 2021 | 1,758 | 4,428,407 (11%) | 0% | 9.0 | 15,847 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 9.91 per share. | 03 May 2021 | 417 | 68,375 (0%) | 0% | 9.9 | 4,133 | COMMON STOCK |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 9.91 per share. | 03 May 2021 | 152 | 68,370 (0%) | 0% | 9.9 | 1,506 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 9.80 per share. | 05 Apr 2021 | 1,584 | 4,430,165 (11%) | 0% | 9.8 | 15,528 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 9.80 per share. | 05 Apr 2021 | 426 | 121,662 (0%) | 0% | 9.8 | 4,176 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 9.80 per share. | 05 Apr 2021 | 426 | 68,792 (0%) | 0% | 9.8 | 4,176 | COMMON STOCK |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 9.80 per share. | 05 Apr 2021 | 155 | 68,522 (0%) | 0% | 9.8 | 1,519 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.14 per share. | 02 Mar 2021 | 1,238 | 4,431,749 (11%) | 0% | 10.1 | 12,556 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.15 per share. | 02 Mar 2021 | 422 | 122,088 (0%) | 0% | 10.1 | 4,283 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 10.16 per share. | 02 Mar 2021 | 422 | 69,218 (0%) | 0% | 10.2 | 4,288 | COMMON STOCK |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 10.14 per share. | 02 Mar 2021 | 154 | 68,677 (0%) | 0% | 10.1 | 1,561 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2021 | 149,951 | 4,432,987 (11%) | 0% | 0 | COMMON STOCK | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2021 | 210,944 | 210,944 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2021 | 74,341 | 74,341 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2021 | 52,846 | 122,510 (0%) | 0% | 0 | COMMON STOCK | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2021 | 19,757 | 69,640 (0%) | 0% | 0 | COMMON STOCK | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2021 | 27,793 | 27,793 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2021 | 55,595 | 68,831 (0%) | 0% | 0 | COMMON STOCK | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2021 | 78,209 | 78,209 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2021 | 36,069 | 36,069 (0%) | 0% | 0 | COMMON STOCK | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 12.22 per share. | 02 Feb 2021 | 1,222 | 4,283,036 (10%) | 0% | 12.2 | 14,931 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 12.23 per share. | 02 Feb 2021 | 415 | 69,664 (0%) | 0% | 12.2 | 5,076 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 12.27 per share. | 02 Feb 2021 | 412 | 49,883 (0%) | 0% | 12.3 | 5,054 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 12.26 per share. | 02 Feb 2021 | 179 | 13,236 (0%) | 0% | 12.3 | 2,195 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.22 per share. | 04 Jan 2021 | 18,235 | 4,284,258 (10%) | 0% | 10.2 | 186,380 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.23 per share. | 04 Jan 2021 | 6,548 | 70,079 (0%) | 0% | 10.2 | 67,016 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 10.23 per share. | 04 Jan 2021 | 6,463 | 50,295 (0%) | 0% | 10.2 | 66,145 | Common Stock |
| Maximo F. Nougues | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 10.22 per share. | 04 Jan 2021 | 2,145 | 13,415 (0%) | 0% | 10.2 | 21,930 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 11.66 per share. | 02 Dec 2020 | 355 | 4,302,493 (10%) | 0% | 11.7 | 4,138 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 11.65 per share. | 02 Dec 2020 | 92 | 76,627 (0%) | 0% | 11.7 | 1,072 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 02 Nov 2020 | 371 | 4,302,848 (10%) | 0% | 7.8 | 2,899 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 7.81 per share. | 02 Nov 2020 | 97 | 76,719 (0%) | 0% | 7.8 | 758 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.13 per share. | 02 Oct 2020 | 350 | 4,303,219 (10%) | 0% | 10.1 | 3,545 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.14 per share. | 02 Oct 2020 | 91 | 76,816 (0%) | 0% | 10.1 | 923 | COMMON STOCK |
| Jay M. Moyes | Director | Sale of securities on an exchange or to another person at price $ 10.00 per share. | 16 Sep 2020 | 9,703 | 31,570 (0%) | 0% | 10 | 97,030 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 9.78 per share. | 02 Sep 2020 | 347 | 4,303,569 (10%) | 0% | 9.8 | 3,393 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 9.77 per share. | 02 Sep 2020 | 90 | 76,907 (0%) | 0% | 9.8 | 879 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.79 per share. | 03 Aug 2020 | 330 | 4,303,916 (10%) | 0% | 10.8 | 3,561 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.80 per share. | 03 Aug 2020 | 86 | 76,997 (0%) | 0% | 10.8 | 929 | COMMON STOCK |
| Brian M. Stuglik | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jul 2020 | 93,953 | 93,953 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.66 per share. | 02 Jul 2020 | 2,607 | 4,304,246 (10%) | 0% | 10.7 | 27,803 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.67 per share. | 02 Jul 2020 | 660 | 77,083 (0%) | 0% | 10.7 | 7,040 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 10.69 per share. | 02 Jul 2020 | 572 | 56,758 (0%) | 0% | 10.7 | 6,112 | Common Stock |
| Jay M. Moyes | Director | Sale of securities on an exchange or to another person at price $ 9.50 per share. | 16 Jun 2020 | 9,720 | 41,273 (0%) | 0% | 9.5 | 92,340 | COMMON STOCK |
| Troy E. Wilson | Director | Sale of securities on an exchange or to another person at price $ 9.97 per share. | 11 Jun 2020 | 25,245 | 26,098 (0%) | 0% | 10.0 | 251,693 | COMMON STOCK |
| Adrian Senderowicz | Director | Sale of securities on an exchange or to another person at price $ 9.89 per share. | 11 Jun 2020 | 10,000 | 40,993 (0%) | 0% | 9.9 | 98,878 | COMMON STOCK |
| Michael P Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 25,748 | 50,653 (0%) | 0% | 0 | COMMON STOCK | |
| Jay M. Moyes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 25,748 | 50,993 (0%) | 0% | 0 | COMMON STOCK | |
| Troy E. Wilson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 25,748 | 51,343 (0%) | 0% | 0 | COMMON STOCK | |
| Adrian Senderowicz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 25,748 | 50,993 (0%) | 0% | 0 | COMMON STOCK | |
| Frank Zavrl | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 25,748 | 50,993 (0%) | 0% | 0 | COMMON STOCK | |
| Hugh O'Dowd | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 25,748 | 25,748 (0%) | 0% | 0 | COMMON STOCK | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 25,748 | 25,748 (0%) | 0% | 0 | COMMON STOCK | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.71 per share. | 02 Jun 2020 | 242 | 4,306,853 (10%) | 0% | 10.7 | 2,592 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.70 per share. | 02 Jun 2020 | 100 | 4,307,095 (10%) | 0% | 10.7 | 1,070 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.66 per share. | 02 Jun 2020 | 89 | 77,743 (0%) | 0% | 10.7 | 949 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 9.70 per share. | 04 May 2020 | 339 | 4,307,195 (10%) | 0% | 9.7 | 3,289 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 9.62 per share. | 04 May 2020 | 89 | 77,832 (0%) | 0% | 9.6 | 856 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 7.39 per share. | 02 Apr 2020 | 347 | 4,307,534 (10%) | 0% | 7.4 | 2,563 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 7.37 per share. | 02 Apr 2020 | 91 | 77,921 (0%) | 0% | 7.4 | 671 | COMMON STOCK |
| Jeffrey Jerome Ludwig | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Mar 2020 | 320,000 | 320,000 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.02 per share. | 02 Mar 2020 | 372 | 4,307,881 (10%) | 0% | 10.0 | 3,726 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.02 per share. | 02 Mar 2020 | 96 | 78,012 (0%) | 0% | 10.0 | 962 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 4,500 | 57,330 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2020 | 127,553 | 4,308,253 (10%) | 0% | 0 | COMMON STOCK | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2020 | 161,649 | 161,649 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2020 | 54,842 | 54,842 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2020 | 43,274 | 78,108 (0%) | 0% | 0 | COMMON STOCK | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2020 | 54,842 | 54,842 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2020 | 43,274 | 54,558 (0%) | 0% | 0 | COMMON STOCK | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2020 | 15,560 | 15,560 (0%) | 0% | 0 | COMMON STOCK | |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2020 | 15,567 | 15,567 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 8.02 per share. | 03 Feb 2020 | 331 | 4,180,700 (10%) | 0% | 8.0 | 2,653 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 8.02 per share. | 03 Feb 2020 | 105 | 34,834 (0%) | 0% | 8.0 | 842 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 8.33 per share. | 02 Jan 2020 | 43 | 4,187,004 (10%) | 0% | 8.3 | 358 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 8.39 per share. | 02 Jan 2020 | 5,973 | 4,181,031 (10%) | 0% | 8.4 | 50,113 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 8.40 per share. | 02 Jan 2020 | 1,514 | 34,939 (0%) | 0% | 8.4 | 12,718 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 8.50 per share. | 02 Jan 2020 | 2 | 36,453 (0%) | 0% | 8.5 | 17 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 8.43 per share. | 02 Jan 2020 | 1,405 | 11,284 (0%) | 0% | 8.4 | 11,847 | Common Stock |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.33 per share. | 02 Dec 2019 | 455 | 4,187,047 (10%) | 0% | 10.3 | 4,700 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.34 per share. | 02 Dec 2019 | 83 | 36,455 (0%) | 0% | 10.3 | 858 | COMMON STOCK |
| Ann C. Miller | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Nov 2019 | 125,306 | 125,306 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 7.40 per share. | 04 Nov 2019 | 100 | 4,187,502 (10%) | 0% | 7.4 | 740 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 7.40 per share. | 04 Nov 2019 | 378 | 4,187,602 (10%) | 0% | 7.4 | 2,797 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 7.38 per share. | 04 Nov 2019 | 88 | 36,538 (0%) | 0% | 7.4 | 649 | COMMON STOCK |
| Hugh O'Dowd | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Oct 2019 | 85,201 | 85,201 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 9.97 per share. | 02 Oct 2019 | 504 | 4,187,980 (10%) | 0% | 10.0 | 5,027 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.05 per share. | 02 Oct 2019 | 91 | 36,626 (0%) | 0% | 10.1 | 915 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Sale of securities on an exchange or to another person at price $ 11.42 per share. | 10 Sep 2019 | 1,711 | 12,689 (0%) | 0% | 11.4 | 19,540 | Common Stock |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Sep 2019 | 4,500 | 14,400 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 10.14 per share. | 04 Sep 2019 | 524 | 4,188,484 (10%) | 0% | 10.1 | 5,313 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.11 per share. | 04 Sep 2019 | 95 | 36,717 (0%) | 0% | 10.1 | 960 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 9.00 per share. | 02 Aug 2019 | 1 | 4,189,008 (10%) | 0% | 9 | 9 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 9.03 per share. | 02 Aug 2019 | 516 | 4,189,009 (10%) | 0% | 9.0 | 4,659 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 9.00 per share. | 02 Aug 2019 | 94 | 36,812 (0%) | 0% | 9 | 846 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 9.98 per share. | 22 Jul 2019 | 12,715 | 4,189,525 (10%) | 0% | 10.0 | 126,846 | COMMON STOCK |
| Steven Lo | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 10.04 per share. | 22 Jul 2019 | 1,852 | 19,557 (0%) | 0% | 10.0 | 18,600 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 10.10 per share. | 22 Jul 2019 | 1,841 | 36,906 (0%) | 0% | 10.1 | 18,589 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 12.78 per share. | 02 Jul 2019 | 495 | 4,202,240 (10%) | 0% | 12.8 | 6,326 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 12.78 per share. | 02 Jul 2019 | 89 | 38,747 (0%) | 0% | 12.8 | 1,137 | COMMON STOCK |
| Michael P Miller | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2019 | 19,423 | 24,905 (0%) | 0% | 0 | COMMON STOCK | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2019 | 19,423 | 25,245 (0%) | 0% | 0 | COMMON STOCK | |
| Troy E. Wilson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2019 | 19,423 | 25,595 (0%) | 0% | 0 | COMMON STOCK | |
| Adrian Senderowicz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2019 | 19,423 | 25,245 (0%) | 0% | 0 | COMMON STOCK | |
| Frank Zavrl | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2019 | 19,423 | 25,245 (0%) | 0% | 0 | COMMON STOCK | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 15.18 per share. | 03 Jun 2019 | 483 | 4,202,735 (10%) | 0% | 15.2 | 7,332 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 15.07 per share. | 03 Jun 2019 | 88 | 38,836 (0%) | 0% | 15.1 | 1,326 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 32.38 per share. | 02 May 2019 | 477 | 4,203,218 (10%) | 0% | 32.4 | 15,445 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 32.38 per share. | 02 May 2019 | 85 | 38,924 (0%) | 0% | 32.4 | 2,752 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 35.79 per share. | 02 Apr 2019 | 491 | 4,203,695 (10%) | 0% | 35.8 | 17,573 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 35.78 per share. | 02 Apr 2019 | 88 | 39,009 (0%) | 0% | 35.8 | 3,149 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 38.62 per share. | 04 Mar 2019 | 496 | 4,204,186 (10%) | 0% | 38.6 | 19,156 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 38.66 per share. | 04 Mar 2019 | 88 | 39,097 (0%) | 0% | 38.7 | 3,402 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Feb 2019 | 62,634 | 62,634 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Feb 2019 | 39,215 | 4,204,682 (10%) | 0% | 0 | COMMON STOCK | |
| Steven Lo | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Feb 2019 | 36,300 | 36,300 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Feb 2019 | 9,900 | 39,185 (0%) | 0% | 0 | COMMON STOCK | |
| Richard P. Bryce | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Feb 2019 | 15,400 | 15,400 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Feb 2019 | 15,400 | 15,400 | - | - | Stock Option (Right to Buy) | |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Feb 2019 | 9,900 | 9,900 (0%) | 0% | 0 | Common Stock | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 27.80 per share. | 04 Feb 2019 | 345 | 4,165,467 (10%) | 0% | 27.8 | 9,591 | COMMON STOCK |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 27.64 per share. | 04 Feb 2019 | 87 | 31,957 (0%) | 0% | 27.6 | 2,405 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 27.78 per share. | 04 Feb 2019 | 89 | 29,285 (0%) | 0% | 27.8 | 2,472 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 24.74 per share. | 22 Jan 2019 | 8,825 | 4,165,812 (10%) | 0% | 24.7 | 218,334 | COMMON STOCK |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 24.80 per share. | 22 Jan 2019 | 713 | 32,044 (0%) | 0% | 24.8 | 17,682 | COMMON STOCK |
| Steven Lo | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 24.91 per share. | 22 Jan 2019 | 2,114 | 21,409 (0%) | 0% | 24.9 | 52,664 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 24.72 per share. | 22 Jan 2019 | 1,959 | 29,374 (0%) | 0% | 24.7 | 48,426 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 20.67 per share. | 03 Jan 2019 | 4,424 | 4,174,637 (10%) | 0% | 20.7 | 91,444 | COMMON STOCK |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 20.67 per share. | 03 Jan 2019 | 1,210 | 32,757 (0%) | 0% | 20.7 | 25,011 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 20.67 per share. | 03 Jan 2019 | 1,210 | 31,333 (0%) | 0% | 20.7 | 25,011 | COMMON STOCK |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 22.77 per share. | 03 Dec 2018 | 1,239 | 33,967 (0%) | 0% | 22.8 | 28,212 | COMMON STOCK |
| Maximo F. Nougues | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Nov 2018 | 90,000 | 90,000 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 52.00 per share. | 20 Jul 2018 | 12,520 | 4,179,061 (11%) | 0% | 52.0 | 651,020 | COMMON STOCK |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 51.95 per share. | 20 Jul 2018 | 610 | 35,206 (0%) | 0% | 52.0 | 31,690 | COMMON STOCK |
| Steven Lo | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 51.85 per share. | 20 Jul 2018 | 1,839 | 23,523 (0%) | 0% | 51.9 | 95,360 | COMMON STOCK |
| Richard P. Bryce | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 51.95 per share. | 20 Jul 2018 | 1,836 | 32,543 (0%) | 0% | 52.0 | 95,381 | COMMON STOCK |
| Michael P Miller | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 5,482 | 5,482 (0%) | 0% | 0 | COMMON STOCK | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 5,822 | 5,822 (0%) | 0% | 0 | COMMON STOCK | |
| Troy E. Wilson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 5,822 | 6,172 (0%) | 0% | 0 | COMMON STOCK | |
| Adrian Senderowicz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 5,822 | 5,822 (0%) | 0% | 0 | COMMON STOCK | |
| Frank Zavrl | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 5,822 | 5,822 (0%) | 0% | 0 | COMMON STOCK | |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 53.00 per share. | 01 Jun 2018 | 1,211 | 35,816 (0%) | 0% | 53 | 64,183 | COMMON STOCK |
| Michael P Miller | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2018 | 17,626 | 17,626 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2018 | 56,940 | 56,940 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2018 | 35,650 | 4,191,581 (11%) | 0% | 0 | COMMON STOCK | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2018 | 9,000 | 37,027 (0%) | 0% | 0 | COMMON STOCK | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2018 | 14,000 | 14,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Steven Lo | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2018 | 33,000 | 33,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2018 | 9,000 | 34,379 (0%) | 0% | 0 | COMMON STOCK | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 92.75 per share. | 22 Jan 2018 | 10,692 | 4,155,931 (11%) | 0% | 92.8 | 991,683 | COMMON STOCK |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 92.85 per share. | 22 Jan 2018 | 669 | 28,027 (0%) | 0% | 92.9 | 62,117 | COMMON STOCK |
| Steven Lo | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 92.85 per share. | 22 Jan 2018 | 1,858 | 25,362 (0%) | 0% | 92.8 | 172,515 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Sale of securities on an exchange or to another person at price $ 92.75 per share. | 22 Jan 2018 | 1,860 | 25,379 (0%) | 0% | 92.8 | 172,515 | COMMON STOCK |
| Douglas M. Hunt | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2018 | 90,000 | 90,000 | - | - | Stock Option (Right to Buy) | |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 105.46 per share. | 01 Dec 2017 | 1,322 | 28,696 (0%) | 0% | 105.5 | 139,424 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Sep 2017 | 15,000 | 67,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.30 per share. | 29 Sep 2017 | 15,000 | 42,239 (0%) | 0% | 11.3 | 169,500 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Sale of securities on an exchange or to another person at price $ 120.00 per share. | 29 Sep 2017 | 15,000 | 27,239 (0%) | 0% | 120 | 1,800,000 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.30 per share. | 06 Sep 2017 | 1,000 | 28,239 (0%) | 0% | 11.3 | 11,300 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Sep 2017 | 1,000 | 96,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Sep 2017 | 14,000 | 82,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Sale of securities on an exchange or to another person at price $ 100.10 per share. | 06 Sep 2017 | 14,000 | 27,239 (0%) | 0% | 100.1 | 1,401,400 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.30 per share. | 06 Sep 2017 | 14,000 | 41,239 (0%) | 0% | 11.3 | 158,200 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Sale of securities on an exchange or to another person at price $ 100.00 per share. | 06 Sep 2017 | 1,000 | 27,239 (0%) | 0% | 100 | 100,000 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 94.34 per share. | 20 Jul 2017 | 9,175 | 4,170,623 (11%) | 0% | 94.3 | 865,605 | COMMON STOCK |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 95.60 per share. | 20 Jul 2017 | 4,000 | 4,166,623 (11%) | 0% | 95.6 | 382,400 | COMMON STOCK |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 95.15 per share. | 20 Jul 2017 | 662 | 30,018 (0%) | 0% | 95.2 | 62,991 | COMMON STOCK |
| Steven Lo | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 94.90 per share. | 20 Jul 2017 | 1,990 | 27,220 (0%) | 0% | 94.9 | 188,853 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Sale of securities on an exchange or to another person at price $ 95.14 per share. | 20 Jul 2017 | 7 | 27,239 (0%) | 0% | 95.1 | 666 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Sale of securities on an exchange or to another person at price $ 94.48 per share. | 20 Jul 2017 | 1,991 | 27,246 (0%) | 0% | 94.5 | 188,111 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jul 2017 | 5,000 | 97,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 11.30 per share. | 03 Jul 2017 | 5,000 | 34,237 (0%) | 0% | 11.3 | 56,500 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Sale of securities on an exchange or to another person at price $ 87.10 per share. | 03 Jul 2017 | 5,000 | 29,237 (0%) | 0% | 87.1 | 435,500 | COMMON STOCK |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2017 | 7,604 | 7,604 | - | - | Stock Option (Right to Buy) | |
| Troy E. Wilson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2017 | 7,604 | 7,604 | - | - | Stock Option (Right to Buy) | |
| Adrian Senderowicz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2017 | 7,604 | 7,604 | - | - | Stock Option (Right to Buy) | |
| Frank Zavrl | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2017 | 7,604 | 7,604 | - | - | Stock Option (Right to Buy) | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2017 | 21,000 | 30,680 (0%) | 0% | 0 | COMMON STOCK | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2017 | 70,000 | 70,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2017 | 31,500 | 31,500 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Steven Lo | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2017 | 31,500 | 31,500 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2017 | 31,500 | 31,500 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Robert Charnas | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2017 | 15,750 | 15,750 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 33.24 per share. | 20 Jan 2017 | 10,202 | 4,179,798 (11%) | 0% | 33.2 | 339,064 | COMMON STOCK |
| Charles R. Eyler | SEE REMARKS | Sale of securities on an exchange or to another person at price $ 33.24 per share. | 20 Jan 2017 | 820 | 9,680 (0%) | 0% | 33.2 | 27,253 | COMMON STOCK |
| Steven Lo | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 33.23 per share. | 20 Jan 2017 | 2,290 | 29,210 (0%) | 0% | 33.2 | 76,108 | COMMON STOCK |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Sale of securities on an exchange or to another person at price $ 33.24 per share. | 20 Jan 2017 | 2,293 | 29,237 (0%) | 0% | 33.2 | 76,208 | COMMON STOCK |
| Robert Charnas | Other | Sale of securities on an exchange or to another person at price $ 33.23 per share. | 20 Jan 2017 | 2,239 | 29,461 (0%) | 0% | 33.2 | 74,413 | COMMON STOCK |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Troy E. Wilson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Adrian Senderowicz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Frank Zavrl | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Nov 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Oct 2016 | 150,000 | 4,190,000 | - | - | COMMON STOCK | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Oct 2016 | 10,500 | 10,500 | - | - | Common Stock | |
| Steven Lo | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Oct 2016 | 31,500 | 31,500 | - | - | COMMON STOCK | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Oct 2016 | 31,500 | 31,530 | - | - | COMMON STOCK | |
| Robert Charnas | Other | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Oct 2016 | 31,500 | 31,700 | - | - | COMMON STOCK | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2016 | 66,667 | 66,667 | - | - | Stock Option (Right to Buy) | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2016 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Steven Lo | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2016 | 30,000 | 30,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2016 | 41,250 | 41,250 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard B. Phillips | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Apr 2016 | 25,000 | 25,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Adrian Senderowicz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Apr 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Frank Zavrl | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Apr 2016 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Troy E. Wilson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Adrian Senderowicz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 10,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Frank Zavrl | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 10,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Oct 2015 | 31,500 | 31,500 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Oct 2015 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Steven Lo | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Sep 2015 | 150,000 | 150,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Troy E. Wilson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Sep 2015 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Adrian Senderowicz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Sep 2015 | 10,000 | 10,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Frank Zavrl | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Sep 2015 | 10,000 | 10,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Frank Zavrl | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Sep 2015 | 30,000 | 30,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Aug 2015 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Adrian Senderowicz | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Aug 2015 | 30,000 | 30,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Aug 2015 | 31,500 | 31,500 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jul 2015 | 3,000 | 102,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 06 Jul 2015 | 3,000 | 30 | - | - | COMMON STOCK | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jul 2015 | 3,000 | 3,030 | - | - | COMMON STOCK | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2014 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2014 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy | |
| Thomas R. Malley | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2014 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Troy E. Wilson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2014 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Nov 2014 | 31,500 | 31,500 | - | - | Stock Option (Right to Buy) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2014 | 31,500 | 31,500 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Apr 2014 | 2 | 2 | - | - | COMMON STOCK | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Apr 2014 | 28 | 30 | - | - | COMMON STOCK | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2013 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Thomas R. Malley | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2013 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Troy E. Wilson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Dec 2013 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2013 | 31,500 | 31,500 | - | - | Stock Option (Right to Buy) | |
| Richard B. Phillips | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Nov 2013 | 31,500 | 31,500 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Oct 2013 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Troy E. Wilson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Oct 2013 | 40,000 | 40,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jul 2013 | 36,750 | 36,750 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Alan H. Auerbach | Director, PRESIDENT AND CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2012 | 150,000 | 150,000 | - | - | Stock Option (Right to Buy) | |
| Charles R. Eyler | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2012 | 22,500 | 22,500 | - | - | Stock Option (Right to Buy) | |
| Richard B. Phillips | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Dec 2012 | 31,500 | 31,500 | - | - | Stock Option (Right to Buy) | |
| Alan H. Auerbach | Director, PRESIDENT, CEO & SECRETARY, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Oct 2012 | 2,116,250 | 2,116,250 | - | - | Warrant to Purchase Common Stock | |
| Thomas R. Malley | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 24 Oct 2012 | 10,000 | 156,551 | - | - | COMMON STOCK | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Oct 2012 | 20,000 | 20,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Oct 2012 | 20,000 | 20,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Thomas R. Malley | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Oct 2012 | 10,000 | 10,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Thomas R. Malley | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Oct 2012 | 10,000 | 10,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Richard P. Bryce | SR VP, CLINICAL RESEARCH & DEV | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Jun 2012 | 105,000 | 105,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Thomas R. Malley | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 11 Jun 2012 | 10,032 | 146,551 | - | - | COMMON STOCK | |
| Thomas R. Malley | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Jun 2012 | 8,168 | 136,519 | - | - | COMMON STOCK | |
| Thomas R. Malley | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 07 Jun 2012 | 1,800 | 128,351 | - | - | COMMON STOCK | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2012 | 30,000 | 30,000 | - | - | STOCK OPTION (RIGHT TO BUY) | |
| Jay M. Moyes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Apr 2012 | 10,000 | 10,000 | - | - | STOCK OPTION (RIGHT TO BUY) |